Skin Boosters Compared: Profhilo vs Polynucleotides
Not all injectables are about adding volume. For many patients, the goal is to enhance skin quality by hydrating, firming, and rejuvenating the complexion from within. That’s where skin boosters come in.
At The Aesthetics Doctor, Dr Ahmed offers advanced skin rejuvenation treatments including Profhilo and polynucleotides. Both are injectable treatments with minimal downtime, but they work in different ways to target different concerns. In this guide, we’ll explore how they compare and how each can support long-term skin health.
What Are Skin Boosters?
Skin boosters are injectable skin treatments that focus on improving hydration, elasticity, and texture. Unlike hyaluronic acid fillers, they do not add volume or alter facial structure. Instead, they work in harmony with your skin’s physiology to stimulate collagen production, support tissue repair, and restore a natural glow.
Common concerns treated with skin boosters include:
- Dull or dehydrated skin
- Fine lines or crepey texture
- Loss of firmness and skin elasticity
- Uneven skin tone
- Early signs of skin ageing
Skin boosters can be used across the face, neck, chest and hands, in any area where the skin needs a boost in hydration or regenerative support.
Polynucleotides: Regeneration and Repair for Delicate Skin
Polynucleotides are wound healing agents derived from purified DNA fragments. They work by supporting tissue repair and reducing inflammation, making them a popular choice for skin that is thin, sensitive, or showing signs of ageing.
Polynucleotide skin boosters help with:
• Collagen stimulation through fibroblast activation
• Repairing damaged or inflamed skin
• Supporting wound healing and tissue regeneration
• Improving elasticity and fine lines
They are particularly useful for areas such as the under-eyes, neck and around the mouth, where skin is more fragile and prone to ageing. Polynucleotides focus more on regeneration, while Profhilo is primarily used to improve hydration.
Profhilo: Deep Hydration with Hyaluronic Acid
Profhilo is an injectable skin treatment made from highly concentrated, pure hyaluronic acid. It spreads beneath the skin like honey, stimulating hydration and supporting collagen and elastin production.
Profhilo is especially effective for:
• Skin hydration at a deep level
• Improved firmness and lax skin
• A brighter, more radiant skin tone
• Giving the skin a plump, dewy look
Profhilo is typically delivered across five injection points per side of the face and is suitable for treating the neck, décolletage and hands as well as the face.
Treatment Sessions and What to Expect
Both treatments are quick, non-invasive, and suitable for patients seeking cosmetic enhancements without altering facial expressions or contours.
- Profhilo results typically begin after the first session, with full skin hydration and firmness seen after two sessions. Effects last up to 6 months.
- Polynucleotide treatments build gradually over time, improving elasticity and reducing inflammation. Maintenance sessions are usually required every 6 months.
There is minimal downtime. You may notice small bumps, redness, or slight swelling at the injection sites, but these usually resolve within hours.
How to Choose the Right Skin Booster
Your personalised skin booster plan depends on:
• Skin type and texture
• Ageing concerns
• Treatment history
• Desired outcome
During your consultation, Dr Ahmed will assess your skin health, discuss treatment goals, and guide you towards the most effective treatments based on clinical insight and patient safety.
Key Differences: Profhilo vs Polynucleotides
While both treatments improve skin quality, each has a unique mode of action and suits different goals. Here’s how they compare:
Profhilo
• Active ingredient: Hyaluronic acid
• Primary function: Skin hydration, elasticity, improved firmness
• Best for: Dull skin, dehydrated skin, lax skin
• Common treatment areas: Face, neck, chest, hands
• Recommended sessions: Usually two, spaced four weeks apart
• Result timeline: Full results visible around 4–6 weeks
• Suitable for: General skin rejuvenation, early signs of ageing
Polynucleotides
• Active ingredient: DNA-based wound healing agents
• Primary function: Cellular repair, regeneration, collagen stimulation
• Best for: Thin or inflamed skin, skin with oxidative stress
• Common treatment areas: Under-eye region, neck, peri-oral areas
• Recommended sessions: Usually three to four, depending on concern
• Result timeline: Gradual improvement over several weeks
• Suitable for: Sensitive skin types, post-inflammatory concerns
Dr Ahmed may recommend one or both treatments depending on your skin’s needs. In some cases, combining them can enhance results by using Profhilo for hydration and polynucleotides to support more delicate areas.
Book a Consultation
Whether you are looking for a quick boost in hydration or a regenerative solution for tired, delicate skin, Profhilo and polynucleotides offer a range of benefits. Both treatments support skin rejuvenation, collagen production, and a smoother, more radiant complexion with minimal disruption to your routine.
Book your consultation with Dr Ahmed at The Aesthetics Doctor to explore your options and discover which skin booster treatment aligns with your skin goals.
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