Ameela Exosomes Treatment

Ameela Exosomes deliver a multi-phase regenerative cascade, acting across different cellular pathways to achieve visible results: 

Initiation phase - Reset inflammation 

Grapefruit and Watermelon Exosomes carry antioxidant-rich mRNA and lipids, reducing oxidative stress and inhibiting inflammatory cytokines (TNF-α, IL-6). This prepares the skin for deeper stimulation and tissue regeneration. 

Activation phase - DNA repair and angiogenesis 

Ameela Polynucleotides, extracted from Wild Salmon DNA through a pharmaceutical-grade purification process, bind to cell receptors. With their low molecular weight, they penetrate effectively to trigger angiogenesis, vascularization, and enhanced fibroblast activity. 

Growth factor phase - Multi-Layer Renewal 

A complex of Bio-Mimetic Growth Factors (EGF, IGF-1, bFGF, VEGF, TGF-β) drives proliferation of skin cells, stimulates collagen and elastin, and supports stem cells and endothelial cells for improved repair. This cascade strengthens dermal architecture and improves the efficacy of collagen regeneration. In addition to the Bio-Mimetic Growth Factors, the treatment includes advanced Peptides that further support dermal regeneration and structural integrity. These peptides work synergistically with exosomes and polynucleotides to stimulate collagen production and improve overall skin function.

Modulation phase - Wrinkle softening 

Hexapeptide-8 reduces expression lines by interrupting SNARE complex formation, mimicking the mechanism of botulinum toxin. This gently relaxes facial tension around the forehead and eyes without loss of natural expression.

Integration phase - Barrier reinforcement 

Ameela Collagen improves dermal density, hydration, and stability. Acting as a 3D scaffold, it locks in water, anchors peptides, and supports long-term resilience by protecting collagen from enzyme-driven degradation. Together with peptides and growth factors, Ameela Collagen enhances the treatment’s long-term regenerative effects.

Your treatment begins with a consultation with one of our experienced doctors, who will assess your skin concerns and discuss your treatment options. A personalised plan is created based on your skin health, priorities, and long-term goals.

During the procedure, a carefully formulated blend of actives is applied using a light, hydrating gel designed to optimise skin penetration. The formulation includes polynucleotides, plant-derived exosomes, bio-mimetic growth factors, peptides, collagen-supporting compounds, and hexapeptide-8, working together to support skin regeneration and repair.

Once applied, the active ingredients interact with skin cell receptors to reduce oxidative stress and inflammation, while stimulating key regenerative pathways. This process encourages fibroblast activity, supports collagen synthesis, and helps restore skin elasticity and resilience.

Most patients describe the treatment as comfortable and relaxing. Immediately afterwards, the skin often feels refreshed and hydrated. Visible improvements — including smoother texture, improved luminosity, and softening of fine lines — develop gradually over the following weeks as the skin continues to regenerate.

For optimal results, a course of treatments is usually recommended, with maintenance sessions every 6–9 months to support long-term skin quality, tone, and resilience. 

Ameela Exosomes with Polynucleotides can be used to improve:

• Fine lines and dynamic wrinkles, including forehead lines and peri-orbital areas 
• Uneven skin tone and rough texture 
• Signs of environmental damage, oxidative stress, and ageing 
• Reduced elasticity, firmness, and hydration 
• Skin recovery and healing following other aesthetic procedures

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Any questions or concerns you have around aesthetic treatments, please let us know.